Tslc1 (Nectin-Like Molecule-2) Is Essential for Spermatozoa Motility and Male Fertility
نویسندگان
چکیده
منابع مشابه
Tslc1 (nectin-like molecule-2) is essential for spermatozoa motility and male fertility.
The nectin-like molecule-2 (TSLC1) is a cell-cell adhesion molecule expressed in testicular germ cells. To directly examine the role of Tslc1 in male fertility, we generated Tslc1+/- mice that have greater than 90% reduction in Tslc1 expression. Tslc1+/- males exhibited reduced fertility and rarely transmitted the Tslc1 mutant allele, whereas Tslc1+/- females were consistently able to transmit ...
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ژورنال
عنوان ژورنال: Journal of Andrology
سال: 2006
ISSN: 0196-3635
DOI: 10.2164/jandrol.106.000398